Infections caused by Gram-positive and Gram-negative bacteria encompass a wide spectrum of diseases, each with its unique challenges and implications for treatment. The classification into Gram-positive or Gram-negative is based on the bacteria’s cell wall structure, which influences their response to antibiotics. These infections are of particular concern due to the increasing prevalence of antibiotic resistance, making some traditional treatments less effective.

DeNovaMed’s Technological Approach: At DeNovaMed, our technological innovations are tailored to address the complexities of both Gram-positive and Gram-negative infections. Central to our approach is the strategic targeting of bacterial lipid metabolism – a universal and essential pathway in bacteria. By focusing on the enzymes involved in this pathway, we aim to disrupt the bacteria’s ability to maintain its cell membrane, thereby eradicating the infection.